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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-2-PPA
2-PPA

Chemical Structure : 2-PPA

CAS No.: 21203-86-1

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2-PPA

货号: PC-22928Not For Human Use, Lab Use Only.

2-PPA is a selective TMEM175 inhibitor with IC50 of 31 uM, 26-fold selectivity for TMEM175 compared to hKv3.1, increases lysosomal degradative activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

2-PPA is a selective TMEM175 inhibitor with IC50 of 31 uM, 26-fold selectivity for TMEM175 compared to hKv3.1, increases lysosomal degradative activity.

物理化学性质&存储条件

分子量 170.22
分子式 C11H10N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-phenylpyridin-4-ylamine

参考文献

1. SeCheol Oh, et al. J Am Chem Soc. 2024 Aug 8. doi: 10.1021/jacs.4c05623.

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