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首页-小分子抑制剂&激动剂-Epigenetics-DNA Methyltransferase (DNMT)-2,4-lutidine
2,4-lutidine

Chemical Structure : 2,4-lutidine

CAS No.: 108-47-4

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2,4-lutidine

货号: PC-72251Not For Human Use, Lab Use Only.

2,4-lutidine is a small molecule targeting the UHRF1 tandem Tudor domain (TTD) with TR-FRET (His6-TTD vs. H3K9me3) EC50 of 29.2 uM.

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100 mg ￥3880 In stock
500 mg ￥6880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

2,4-lutidine is a small molecule targeting the UHRF1 tandem Tudor domain (TTD) with TR-FRET (His6-TTD vs. H3K9me3) EC50 of 29.2 uM.
2,4-Lutidine inhibits H3K9me3 peptide binding to TTD-PHD and full length UHRF1, also inhibits TTD-PHD and UHRF1-FL activities.

物理化学性质&存储条件

分子量 107.156
分子式 C7H9N
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,4-lutidine

参考文献

1. Lyra Chang, et al. Sci Rep. 2021 Jan 13;11(1):1121.

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