1V209 | TLR7 agonist | Probechem Biochemicals

Chemical Structure : 1V209

CAS No.: 1062444-54-5

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1V209 (TLR7 agonist 1V209, TLR7 agonist T7)

货号: PC-73063Not For Human Use, Lab Use Only.

1V209 is a synthetic small molecule TLR7 specific ligand and agonist.

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10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

1V209 is a synthetic small molecule TLR7 specific ligand and agonist.
1V209 can be stably conjugated to primary amine functionalized Ficoll or dextran using benzoic acid functional groups.
1V209 conjugated to silica nanoshells is capable of activating an inflammasome pathway to enhance both innate immune-stimulatory and adjuvant potencies of the TLR7 agonist, thereby broadening applications of innate immune stimulators.

物理化学性质&存储条件

分子量	359.342
分子式	C16H17N5O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((6-amino-8-hydroxy-2-(2-methoxyethoxy)-9H-purin-9-yl)methyl)benzoic acid

参考文献

1. Shinchi H, et al. Bioconjug Chem. 2015 Aug 19;26(8):1713-23.

2. Huang CH, et al. ACS Appl Mater Interfaces. 2019 Jul 31;11(30):26637-26647.

3. Baba A, et al. Bioorg Med Chem Lett. 2020 Feb 1;30(3):126840.

1V209 (TLR7 agonist 1V209, TLR7 agonist T7)

生物&药学活性

物理化学性质&存储条件

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1V209 (TLR7 agonist 1V209, TLR7 agonist T7)

生物&药学活性

物理化学性质&存储条件

参考文献

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