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15-LOX-1 inhibitor 5i

Chemical Structure : 15-LOX-1 inhibitor 5i

CAS No.:

15-LOX-1 inhibitor 5i

货号: PC-24322Not For Human Use, Lab Use Only.

15-LOX-1 inhibitor 5i is a potent, selective inhibitor of 15-lipoxygenase-1 (15-LOX-1) with IC50 of 1.7 uM, inhibits lipid peroxidation and protects cells from RSL3-induced cell death.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

15-LOX-1 inhibitor 5i is a potent, selective inhibitor of 15-lipoxygenase-1 (15-LOX-1) with IC50 of 1.7 uM, inhibits lipid peroxidation and protects cells from RSL3-induced cell death.

物理化学性质&存储条件

分子量 354.92
分子式 C22H27ClN2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((6-chloro-2-phenyl-1H-indol-3-yl)methyl)heptan-1-amine

参考文献

1. Zhang J, et al. Eur J Med Chem. 2025 Mar 19;290:117517.

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