1-Piperidine Propionic Acid | PAR2 inhibitor | Probechem Biochemicals

Chemical Structure : 1-Piperidine Propionic Acid

CAS No.: 26371-07-3

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1-Piperidine Propionic Acid (1-PPA)

货号: PC-21762Not For Human Use, Lab Use Only.

1-Piperidine Propionic Acid (1-PPA) is an allosteric Inhibitor of protease activated receptor-2 (PAR2) with IC50 of 2.3 uM.

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25 mg	￥1980	In stock
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生物&药学活性

1-Piperidine Propionic Acid (1-PPA) is an allosteric Inhibitor of protease activated receptor-2 (PAR2) with IC50 of 2.3 uM.
1-PPA binds PAR2 in an allosteric pocket of the receptor inactive conformation.
1-PPA reduces platelet aggregation, inhibits the PAR2-C/EBP-β-SerpinB3 axis and protects from NASH development and progression.

物理化学性质&存储条件

分子量	157.21
分子式	C8H15NO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(piperidin-1-yl)propanoic acid

参考文献

1. Villano Gianmarco, et al. Mol Metab. 2024 Feb 1:81:101889.

2. Chinellato M, et al. Pharmaceuticals (Basel). 2023 Oct 18;16(10):1486.

1-Piperidine Propionic Acid (1-PPA)

生物&药学活性

物理化学性质&存储条件

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1-Piperidine Propionic Acid (1-PPA)

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物理化学性质&存储条件

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