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1-Naphthyl PP1 hydrochloride

Chemical Structure : 1-Naphthyl PP1 hydrochloride

CAS No.: 956025-47-1

1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride)

货号: PC-43793Not For Human Use, Lab Use Only.

A potent Src family kinases with IC50 of 1.0/0.6/0.6 uM for v-Sr/c-Fyn/c-Abl.

规格 价格 库存 数量
10 mg ¥1056.0 In stock
50 mg ¥4248.0 In stock
100 mg ¥7200 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A potent Src family kinases with IC50 of 1.0/0.6/0.6 uM for v-Sr/c-Fyn/c-Abl; less potent for CDK2 and CaMK II; also inhibits Kin28 and Srb10 kinases; potently blocks prostate cancer cell proliferation by inducing G2/M arrest.

物理化学性质&存储条件

分子量 353.8486
分子式 C19H20ClN5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 73 mg/mL

Chemical Name/SMILES

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-, hydrochloride (1:1)

参考文献

1. Bishop AC, et al. Nature. 2000 Sep 21;407(6802):395-401.

2. Kanin EI, et al. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5812-7.

3. Liu Y, et al. Mol Cell Biol. 2004 Feb;24(4):1721-35.

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