Chemical Structure : 1-AM
货号: PC-61202Not For Human Use, Lab Use Only.
1-AM (1_AM) is a potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.
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1-AM (1_AM) is a potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.
分子量 | 510.998 | |
分子式 | C26H28ClFN6O2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Zeng M, et al. Cell Chem Biol. 2017 Aug 17;24(8):1005-1016.e3.
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