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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-019854-B06
019854-B06

Chemical Structure : 019854-B06

CAS No.:

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019854-B06

货号: PC-25848Not For Human Use, Lab Use Only.

019854-B06 is a potent tat-binding antiretroviral compound with IC50 of 1.4 and 0.83 uM in F-Luc activity and HIV-1 infection assays, inhibits Tat-dependent transcription phase, shows binding affinity (KD) of 33.5 uM to Tat peptide.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

019854-B06 is a potent tat-binding antiretroviral compound with IC50 of 1.4 and 0.83 uM in F-Luc activity and HIV-1 infection assays, inhibits Tat-dependent transcription phase, shows binding affinity (KD) of 33.5 uM to Tat peptide.

物理化学性质&存储条件

分子量 454.61
分子式 C28H38O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

methyl (E)-2-(2-((4-(decyloxy)phenoxy)methyl)phenyl)-3-methoxyacrylate

参考文献

1. Shin Y, et al. Biochemistry. 2025 Nov 28. doi: 10.1021/acs.biochem.5c00203.

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