(±)-BI-D |CAS:1416258-16-6 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-(±)-BI-D

Chemical Structure : (±)-BI-D

CAS No.: 1416258-16-6

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(±)-BI-D

货号: PC-45473Not For Human Use, Lab Use Only.

(±)-BI-D is a potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.

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10 mg	￥4280	In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

(±)-BI-D is a potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.
(±)-BI-D inhibits the replication of NL4.3 virus (T124/T125) with EC50 of 51 nM.

物理化学性质&存储条件

分子量	405.4862
分子式	C25H27NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Quinolineacetic acid, 4-(3,4-dihydro-2H-1-benzopyran-6-yl)-α-(1,1-dimethylethoxy)-2-methyl-

参考文献

1. Fader LD, et al. ACS Med Chem Lett. 2014 Apr 16;5(6):711-6.

2. Wang H, et al. Nucleic Acids Res. 2012 Dec;40(22):11518-30.

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(±)-BI-D

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