(S)93-31 | GluN2B antagonist | Probechem Biochemicals

Chemical Structure : (S)93-31

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(S)93-31 ((S) 93-31)

货号: PC-61239Not For Human Use, Lab Use Only.

(S)93-31 is a pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM).

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(S)93-31 is a pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM).
(S)93-31 maximizes neuroprotection in ischemic tissue while minimizing on-target side effects associated with NMDAR blockade in noninjured brain regions.

物理化学性质&存储条件

分子量	489.452
分子式	C22H30Cl2N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(4-(3-(butyl(3,4-dichlorophenethyl)amino)-2-hydroxypropoxy)phenyl)methanesulfonamide

参考文献

1. Yuan H, et al. Neuron. 2015 Mar 18;85(6):1305-1318.

(S)93-31 ((S) 93-31)

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(S)93-31 ((S) 93-31)

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物理化学性质&存储条件

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