(S)-CKi-1 | Covalent creatine kinase inhibitor | Probechem Biochemicals

Chemical Structure : (S)-CKi-1

CAS No.: 2768295-41-4

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(S)-CKi-1 (CKi-24)

货号: PC-20156Not For Human Use, Lab Use Only.

(S)-CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells.

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2 mg	￥3580	In stock
5 mg	￥5580	In stock
10 mg	￥8980	In stock
25 mg		Get quote
100 mg		Get quote

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生物&药学活性

(S)-CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells.

物理化学性质&存储条件

分子量	254.67
分子式	C11H11ClN2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-(2-chloroacetyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide

参考文献

1. Narek Darabedian, et al. Nat Chem Biol. 2023 Feb 23. doi: 10.1038/s41589-023-01273-x.

(S)-CKi-1 (CKi-24)

生物&药学活性

物理化学性质&存储条件

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(S)-CKi-1 (CKi-24)

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物理化学性质&存储条件

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