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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Cyclooxygenase (COX)-(S)-( )-Ibuprofen
(S)-( )-Ibuprofen

Chemical Structure : (S)-( )-Ibuprofen

CAS No.: 51146-56-6

(S)-( )-Ibuprofen ((S)-Ibuprofen)

货号: PC-45989Not For Human Use, Lab Use Only.

An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form.

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5 g ¥720 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form; also inhibits activation of NF-κB more effectively than (R)-ibuprofen (IC50=62 and 122 uM, respectively).

物理化学性质&存储条件

分子量 206.2808
分子式 C13H18O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

H2O: 1 mg/mL (Need ultrasonic and warming); DMSO: < 0.1 mg/mL

Chemical Name/SMILES

Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-,(αS)-

参考文献

1. Evans AM, et al. Br J Clin Pharmacol. 1991 Feb;31(2):131-8.

2. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.

3. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.

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