(R)-SW203668 | SCD inhibitor | Probechem Biochemicals

Chemical Structure : (R)-SW203668

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(R)-SW203668 ( (−)-SW203668, SCD inhibitor (R)-27)

货号: PC-20382Not For Human Use, Lab Use Only.

(R)-SW203668 (SCD inhibitor (R)-27) is a potent, tumor-specific, irreversible stearoyl CoA desaturase (SCD) inhibitor with high sensitity to H2122 cell (IC50=11 nM).

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100 mg		Get quote

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生物&药学活性

(R)-SW203668 (SCD inhibitor (R)-27) is a potent, tumor-specific, irreversible stearoyl CoA desaturase (SCD) inhibitor with high sensitity to H2122 cell (IC50=11 nM).
(R)-SW203668 shows insensitive (e.g., H1155, IC50>5 uM) NSLCL cell lines.
(R)-SW203668 shows selective and potent cytotoxicity against cancer cell lines expressing cytochrome P450 4F11.

物理化学性质&存储条件

分子量	389.47
分子式	C22H19N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-4-(amino(phenyl)methyl)-N-(6-methoxybenzo[d]thiazol-2-yl)benzamide

参考文献

1. Noelle S Williams, et al. J Med Chem. 2020 Sep 10;63(17):9773-9786.

2. JM, et al. Nat Chem Biol. 2016 Apr;12(4):218-25.

(R)-SW203668 ( (−)-SW203668, SCD inhibitor (R)-27)

生物&药学活性

物理化学性质&存储条件

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(R)-SW203668 ( (−)-SW203668, SCD inhibitor (R)-27)

生物&药学活性

物理化学性质&存储条件

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