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首页-小分子抑制剂&激动剂-Others-Other Targets-(R)-CE3F4
(R)-CE3F4

Chemical Structure : (R)-CE3F4

CAS No.: 1593478-56-8

(R)-CE3F4 (CE3F4 (R)-enantiomer)

货号: PC-63112Not For Human Use, Lab Use Only.

(R)-CE3F4 is a more potent, selective EPAC1 antagonist than the racemic CE3F4 and (S)-CE3F4, displays 10-fold selectivity for EPAC1 over EPAC2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    (R)-CE3F4 is a more potent, selective EPAC1 antagonist than the racemic CE3F4 and (S)-CE3F4, displays 10-fold selectivity for EPAC1 over EPAC2.

    物理化学性质&存储条件

    分子量 351.01
    分子式 C11H10Br2FNO
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-5,7-dibromo-6-fluoro-2-methyl-3,4-dihydroquinoline-1(2H)-carbaldehyde

    参考文献

    1. Courilleau D, et al. Biochem Biophys Res Commun. 2013 Oct 25;440(3):443-8.

    2. Courilleau D, et al. J Biol Chem. 2012 Dec 28;287(53):44192-202.

    3. Brown LM, et al. J Biol Chem. 2014 Mar 21;289(12):8217-30.

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