(R)-Baclofen |CAS:69308-37-8 Probechem Biochemicals

Chemical Structure : (R)-Baclofen

CAS No.: 69308-37-8

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(R)-Baclofen (STX-209, Arbaclofen)

货号: PC-45171Not For Human Use, Lab Use Only.

(R)-Baclofen (STX-209, Arbaclofen) derivative of the neurotransmitter GABA that acts as a GABAB receptor agonist.

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生物&药学活性

(R)-Baclofen (STX-209, Arbaclofen) derivative of the neurotransmitter GABA that acts as a GABAB receptor agonist.
(R)-Baclofen also blocks α2δ subunit-containing voltage-dependent calcium channel (VDCC) with Ki of 156 uM.
(R)-Baclofen is a neurotransmitter inhibitor by blocking the release of excitatory transmitters.
(R)-Baclofen serves as a central nervous system depressant and skeletal muscle relaxant.

物理化学性质&存储条件

分子量	213.6608
分子式	C10H12ClNO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	H2O: 5 mg/mL (Need ultrasonic)
Chemical Name/SMILES	Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, (βR)-

参考文献

1. Zvejniece L, et al. Pharmacol Biochem Behav. 2015 Oct;137:23-9.

2. Carter LP, et al. Pharmacol Ther. 2009 Jan;121(1):100-14.

(R)-Baclofen (STX-209, Arbaclofen)

生物&药学活性

物理化学性质&存储条件

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(R)-Baclofen (STX-209, Arbaclofen)

生物&药学活性

物理化学性质&存储条件

参考文献

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