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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-(R)-BPO-27
(R)-BPO-27

Chemical Structure : (R)-BPO-27

CAS No.: 1415390-47-4

(R)-BPO-27 ((R)-BPO 27;(R)-BPO27)

货号: PC-45711Not For Human Use, Lab Use Only.

(R)-BPO-27, the R enantiomer of BPO-27, CFTR chloride conductance inhibitor with IC50 of 4 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

(R)-BPO-27, the R enantiomer of BPO-27, CFTR chloride conductance inhibitor with IC50 of 4 nM.
BPO-27 S enantiomer is inactive.

物理化学性质&存储条件

分子量 548.3416
分子式 C26H18BrN3O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO

Chemical Name/SMILES

6H-Pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]benzoxazine-2-carboxylic acid, 6-(5-bromo-2-furanyl)-7,8,9,10-tetrahydro-7,9-dimethyl-8,10-dioxo-11-phenyl-, (6R)-

参考文献

1. Snyder DS, et al. J Med Chem. 2011 Aug 11;54(15):5468-77.

2. Snyder DS, et al. ACS Med Chem Lett. 2013 May 9;4(5):456-459.

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