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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-(R)-(-)-Rolipram
(R)-(-)-Rolipram

Chemical Structure : (R)-(-)-Rolipram

CAS No.: 85416-75-7

(R)-(-)-Rolipram ((R)-Rolipram;(-)-Rolipram)

货号: PC-45081Not For Human Use, Lab Use Only.

A more active enantiomer of the PDE4 inhibitor rolipram.

规格 价格 库存 数量
50 mg ¥3120 In stock
250 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A more active enantiomer of the PDE4 inhibitor rolipram; shows 2-10-fold more potent than the S-(+) enantiomer rolipram.

Asthma

Phase 2 Clinical

物理化学性质&存储条件

分子量 275.3428
分子式 C16H21NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 49 mg/mL

Chemical Name/SMILES

2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4R)-

参考文献

1. Schneider HH, et al. Eur J Pharmacol. 1986 Aug 7;127(1-2):105-15.

2. Owens RJ, et al. Biochem J. 1997 Aug 15;326 ( Pt 1):53-60.

3. Ohsawa F, et al. Jpn J Pharmacol. 1998 Jun;77(2):147-54.

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