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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-(R)-(-)-JQ1 Enantiomer
(R)-(-)-JQ1 Enantiomer

Chemical Structure : (R)-(-)-JQ1 Enantiomer

CAS No.: 1268524-71-5

(R)-(-)-JQ1 Enantiomer

货号: PC-43339Not For Human Use, Lab Use Only.

(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, (+)-JQ-1 is a potent, specific BET bromodomain BRD4 inhibitor, but (-)-JQ1 has no activity..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, (+)-JQ-1 is a potent, specific BET bromodomain BRD4 inhibitor, but (-)-JQ1 has no activity.

物理化学性质&存储条件

分子量 456.9882
分子式 C23H25ClN4O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, 1,1-dimethylethyl ester, (6R)-

参考文献

1. Filippakopoulos P, et al. Nature. 2010 Dec 23;468(7327):1067-73.

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