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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-(R)-α-methylhistamine
(R)-α-methylhistamine

Chemical Structure : (R)-α-methylhistamine

CAS No.: 75614-89-0

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(R)-α-methylhistamine (RAMH, (R)-(-)-α-Methylhistamine)

货号: PC-28229Not For Human Use, Lab Use Only.

(R)-α-methylhistamine (RAMH, (R)-(-)-α-Methylhistamine) is a potent, selective and brain-penetrant agonist of H3 histamine receptor (H3R) with Kd of 50.3 nM, enhances memory retention and attenuates memory impairment in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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(R)-α-methylhistamine (RAMH, (R)-(-)-α-Methylhistamine) is a potent, selective and brain-penetrant agonist of H3 histamine receptor (H3R) with Kd of 50.3 nM, enhances memory retention and attenuates memory impairment in vivo.

物理化学性质&存储条件

分子量 198.09
分子式 C6H13Cl2N3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-1-(1H-Imidazol-4-yl)propan-2-amine dihydrochloride

参考文献

1. Arrang JM, et al. Nature. 1987 May 14-20;327(6118):117-23.

2. Oishi R, et al. J Neurochem. 1989 May;52(5):1388-92.

3. Li WW, et al. CNS Neurosci Ther. 2014 Sep;20(9):851-9.

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