Chemical Structure : Zolbetuximab
CAS No.: 1496553-00-4
货号: PC-Ab1015Not For Human Use, Lab Use Only.
Zolbetuximab is a first-in-class chimeric IgG1 mAb that specifically binds to Claudin 18 splice variant 2 (CLDN18.2) on the cell surface and mediates cell death through antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Claudin-18 (CLDN18) is a highly specific TJ component of the stomach. It is expressed in foetal and in adult normal gastric mucosa.
规格 | 价格 | 库存 | 数量 |
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1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Zolbetuximab is a first-in-class chimeric IgG1 mAb that specifically binds to Claudin 18 splice variant 2 (CLDN18.2) on the cell surface and mediates cell death through antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Claudin-18 (CLDN18) is a highly specific TJ component of the stomach. It is expressed in foetal and in adult normal gastric mucosa
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Zolbetuximab; IMAB362; Claudiximab; iMAB-362; CLDN18.2; Claudin 18 splice variant 2 |
1. 1, Ajaz A. Bhat, et al. Mol Cancer. 2021; 20: 2. Published online 2021 Jan 4. 2, Oncol Lett. 2020 Jun; 19(6): 3665–3670. 3, Irene Coati, et al. Irene Coati, 4, Türeci Ӧ, et al. Oncoimmunology. 2019; 8(1):e1523096.
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