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STING agonist 1

Chemical Structure : STING agonist 1

CAS No.: 702662-50-8

STING agonist 1 (G10)

货号: PC-45676Not For Human Use, Lab Use Only.

G10 (STING Agonist 1) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

G10 (STING Agonist 1) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts.
G10 (STING Agonist 1) represenst the first synthetic small molecule characterized as an indirect activator of human STING-dependent phenotypes.
G10 (STING Agonist 1) inhibits CHIKV replication in vivo.

物理化学性质&存储条件

分子量 430.8797
分子式 C21H16ClFN2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2H-1,4-Benzothiazine-6-carboxamide, 4-[(2-chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-

参考文献

1. Sali TM, et al. PLoS Pathog. 2015 Dec 8;11(12):e1005324.

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