STIMA 1 |CAS:91634-12-7 Probechem Biochemicals

Chemical Structure : STIMA 1

CAS No.: 91634-12-7

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STIMA 1 (STIMA1)

货号: PC-62083Not For Human Use, Lab Use Only.

STIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro, induces expression of p53 target proteins and triggers apoptosis in mutant p53-expressing human tumor cells..

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25 mg	￥1180	In stock
50 mg	￥1880	In stock
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生物&药学活性

STIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro, induces expression of p53 target proteins and triggers apoptosis in mutant p53-expressing human tumor cells.

物理化学性质&存储条件

分子量	172.187
分子式	C10H8N2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-ethenyl-1H-quinazolin-4-one

参考文献

1. Zache N, et al. Mol Oncol. 2008 Jun;2(1):70-80.

2. Bykov VJ, et al. FEBS Lett. 2014 Aug 19;588(16):2622-7.

STIMA 1 (STIMA1)

生物&药学活性

物理化学性质&存储条件

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STIMA 1 (STIMA1)

生物&药学活性

物理化学性质&存储条件

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