SR-11302 | AP-1 inhibitor | Probechem Biochemicals

Chemical Structure : SR11302

CAS No.: 160162-42-5

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SR11302 (SR 11302, SR-11302)

货号: PC-38608Not For Human Use, Lab Use Only.

SR11302( SR 11302) is a specific, small molecule inhibitor of activator protein-1 (AP-1), inhibits AP-1 activity without activating the transcription of RARE.

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5 mg	￥2880	In stock
10 mg	￥4580	In stock
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100 mg		Get quote

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生物&药学活性

SR11302( SR 11302) is a specific, small molecule inhibitor of activator protein-1 (AP-1), inhibits AP-1 activity without activating the transcription of RARE.
SR11302 inhibits tumor promotion in AP-1-luciferase transgenic mice, inhibits papilloma formation during the course of the tumor promotion.
SR11302 blocks TPA-induced AP-1 transactivation in AP-1-luciferase transgenic mice.
SR11302 decreases VEGF promoter activity and downregulates c-Fos expression and release.
SR11302 reduces metastatic lesion formation in the 4D model of lung cancer.

物理化学性质&存储条件

分子量	376.540
分子式	C26H32O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid

参考文献

1. Maron BA, et al. Circulation. 2014 Jul 8;130(2):168-79.

2. Huang C, et al. Proc Natl Acad Sci U S A. 1997 May 27;94(11):5826-30.

3. Li JJ, et al. Cancer Res. 1997 Aug 15;57(16):3569-76.

4. Catar R, et al. Kidney Int. 2013 Dec;84(6):1119-28.

SR11302 (SR 11302, SR-11302)

生物&药学活性

物理化学性质&存储条件

参考文献

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SR11302 (SR 11302, SR-11302)

生物&药学活性

物理化学性质&存储条件

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