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首页-抗体和重组蛋白-Biosimilar Antibody-Rovalpituzumab
Rovalpituzumab

Chemical Structure : Rovalpituzumab

CAS No.: 1613313-01-1

Rovalpituzumab (Anti-huamn DLL3 mAb, human IgG1-Kappa)

货号: PC-Ab1106Not For Human Use, Lab Use Only.

Rovalpituzumab is the antibody part of Rovalpituzumab tesirine (Rova-T). Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. Rovalpituzumab tesirine (SC16LD6.5) is an antibody-drug conjugate that targets delta-like protein 3 (DLL3) and was initially developed for small cell lung cancer..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Rovalpituzumab is the antibody part of Rovalpituzumab tesirine (Rova-T). Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. Rovalpituzumab tesirine (SC16LD6.5) is an antibody-drug conjugate that targets delta-like protein 3 (DLL3) and was initially developed for small cell lung cancer.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Rovalpituzumab; Anti-human DLL3 antigen; Anti-human Delta-like protein 3; 1613313-01-1

参考文献

1. 1, Rudin CM, et al. Lancet Oncol. 2017 Jan;18(1):42-51. 2, Lashari BH, et al. Drugs R D. 2018 Dec;18(4):255-258. 3, Goldman JW, et al. Clin Transl Sci. 2021 Mar;14(2):664-670.  4, Puca L, et al. Sci Transl Med. 2019 Mar 20;11(484):eaav0891.

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