PF-670462 (PF670462) | CK1ε/CK1δ inhibitor | Probechem Biochemicals

Chemical Structure : PF670462

加入收藏

PF670462 (PF-670462)

货号: PC-49496Not For Human Use, Lab Use Only.

PF-670462 (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively, causes a significant phase delay in animal models of circadian rhythm.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

PF-670462 (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively, causes a significant phase delay in animal models of circadian rhythm.

物理化学性质&存储条件

分子量	337.40
分子式	C19H20FN5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[3-cyclohexyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyrimidin-2-ylamine

参考文献

1. Badura L, et al. J Pharmacol Exp Ther. 2007 Aug;322(2):730-8.

2. Bryant CD, et al. Psychopharmacology (Berl). 2009 May;203(4):703-11.

3. Walton KM, et al. J Pharmacol Exp Ther. 2009 Aug;330(2):430-9.