欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-抗体和重组蛋白-Biosimilar Antibody-Omburtamab
Omburtamab

Chemical Structure : Omburtamab

CAS No.: 1895083-75-6

加入收藏

Omburtamab (Anti-human B7-H3 mAb, human IgG1-Kappa; 8H9)

货号: PC-Ab1066Not For Human Use, Lab Use Only.

8H9 is an IgG1 mAb that targets B7-H3, it is broadly reactive with human solid tumors, including embryonal tumors and carcinomas. 131I-omburtamab, a monoclonal antibody called 8H9 linked to a radioactive agent called iodine 131. 8H9 attaches to B7H3 positive tumor cells in a targeted way and delivers iodine 131 to kill them. 8H9 has been successfully used for radioimmunotherapy for patients with B7-H3(+) tumors. In early phase human clinical trials, 131I-8H9 prolongs survival among high risk pat

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

8H9 is an IgG1 mAb that targets B7-H3, it is broadly reactive with human solid tumors, including embryonal tumors and carcinomas. 131I-omburtamab, a monoclonal antibody called 8H9 linked to a radioactive agent called iodine 131. 8H9 attaches to B7H3 positive tumor cells in a targeted way and delivers iodine 131 to kill them. 8H9 has been successfully used for radioimmunotherapy for patients with B7-H3(+) tumors. In early phase human clinical trials, 131I-8H9 prolongs survival among high risk patients with solid tumors suffering from central nervous system (CNS) metastasis.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Omburtamab; Burtomab; 8H9; B7H3; CD276; CD276 Molecule; 4Ig-B7-H3; B7RP-2; PSEC0249; 1895083-75-6

参考文献

1. 1, Ahmed M, et al. J Biol Chem. 2015 Dec 11;290(50):30018-29. 2, Onda M, et al. Cancer Res. 2004 Feb 15;64(4):1419-24. 3, Modak S, et al. Cancer Res. 2001 May 15;61(10):4048-54. 4, Pandit-Taskar N, et al. J Nucl Med. 2019 Dec;60(12):1794-1801.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: