Chemical Structure : Omburtamab
CAS No.: 1895083-75-6
货号: PC-Ab1066Not For Human Use, Lab Use Only.
8H9 is an IgG1 mAb that targets B7-H3, it is broadly reactive with human solid tumors, including embryonal tumors and carcinomas. 131I-omburtamab, a monoclonal antibody called 8H9 linked to a radioactive agent called iodine 131. 8H9 attaches to B7H3 positive tumor cells in a targeted way and delivers iodine 131 to kill them. 8H9 has been successfully used for radioimmunotherapy for patients with B7-H3(+) tumors. In early phase human clinical trials, 131I-8H9 prolongs survival among high risk pat
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
大包装,大折扣!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
8H9 is an IgG1 mAb that targets B7-H3, it is broadly reactive with human solid tumors, including embryonal tumors and carcinomas. 131I-omburtamab, a monoclonal antibody called 8H9 linked to a radioactive agent called iodine 131. 8H9 attaches to B7H3 positive tumor cells in a targeted way and delivers iodine 131 to kill them. 8H9 has been successfully used for radioimmunotherapy for patients with B7-H3(+) tumors. In early phase human clinical trials, 131I-8H9 prolongs survival among high risk patients with solid tumors suffering from central nervous system (CNS) metastasis.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
|
Chemical Name/SMILES |
Omburtamab; Burtomab; 8H9; B7H3; CD276; CD276 Molecule; 4Ig-B7-H3; B7RP-2; PSEC0249; 1895083-75-6 |
1. 1, Ahmed M, et al. J Biol Chem. 2015 Dec 11;290(50):30018-29. 2, Onda M, et al. Cancer Res. 2004 Feb 15;64(4):1419-24. 3, Modak S, et al. Cancer Res. 2001 May 15;61(10):4048-54. 4, Pandit-Taskar N, et al. J Nucl Med. 2019 Dec;60(12):1794-1801.
备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright