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MitoBloCK 6

Chemical Structure : MitoBloCK 6

CAS No.: 303215-67-0

MitoBloCK 6 (MitoBloCK6)

货号: PC-62048Not For Human Use, Lab Use Only.

MitoBloCK 6 is a small molecule mitochondrial protein import blocker that inhibits Erv1 oxidase activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MitoBloCK 6 is a small molecule mitochondrial protein import blocker that inhibits Erv1 oxidase activity.
MitoBloCK 6 attenuates the import of Erv1 substrates into yeast mitochondria and inhibited oxidation of Tim13 and Cmc1 in in vitro reconstitution assays.
MitoBloCK 6 impairs the cardiac development in zebrafish embryos, induces apoptosis via cytochrome c release in human embryonic stem cells (hESCs) but not in differentiated cells

物理化学性质&存储条件

分子量 357.234
分子式 C19H14Cl2N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,4-dichloro-6-(((4-(phenylamino)phenyl)imino)methyl)phenol

参考文献

1. Dabir DV, et al. Dev Cell. 2013 Apr 15;25(1):81-92.

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