L-Propargylglycine | CSE inhibitor | Probechem Biochemicals

Chemical Structure : L-Propargylglycine

CAS No.: 198774-27-5

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L-Propargylglycine (L-PAG)

货号: PC-72155Not For Human Use, Lab Use Only.

L-Propargylglycine (L-PAG) is the most commonly used, covalently irreversible inhibitor inhibitor of cystathionine γ-lyase (CSE).

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50 mg	￥980	In stock
100 mg	￥1480	In stock
250 mg		Get quote
1 g		Get quote

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生物&药学活性

L-Propargylglycine (L-PAG) is the most commonly used, covalently irreversible inhibitor inhibitor of cystathionine γ-lyase (CSE).
L-Propargylglycine (L-PAG) is also reported to suppress the activity of other B6 enzymes, i.e. aspartate aminotransferase and alanine aminotransferase.
L-Propargylglycine (L-PAG) dose-dependently inhibits endogenous CSE activity and decreases the H2S content in Raw264.7 macrophages with IC50 of 370 uM.

物理化学性质&存储条件

分子量	113.116
分子式	C5H7NO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-Aminopent-4-ynoic acid hydrochloride

参考文献

1. Antonia Asimakopoulou, et al. Br J Pharmacol. 2013 Jun;169(4):922-32.

2. Collin M, et al. Br J Pharmacol. 2005 Oct;146(4):498-505.

3. Bhatia M, et al. Br J Pharmacol. 2005 May;145(2):141-4.

4. Tamizhselvi R, et al. J Cell Mol Med. 2007 Mar-Apr;11(2):315-26.

L-Propargylglycine (L-PAG)

生物&药学活性

物理化学性质&存储条件

参考文献

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L-Propargylglycine (L-PAG)

生物&药学活性

物理化学性质&存储条件

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