JumOCA peptide | OCA-B peptide inhibitor | Probechem Biochemicals

Chemical Structure : JumOCA peptide

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JumOCA peptide (VKELLRRKRGH)

货号: PC-72458Not For Human Use, Lab Use Only.

JumOCA peptide (VKELLRRKRGH) is a peptide corresponding to the transcriptional coregulator OCA-B N terminus, membrane-penetrating OCA-B peptide inhibitor.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

JumOCA peptide (VKELLRRKRGH) is a peptide corresponding to the transcriptional coregulator OCA-B N terminus, membrane-penetrating OCA-B peptide inhibitor.
The transcriptional coregulator OCA-B promotes expression of T cell target genes in cases of repeated antigen exposure, a necessary feature of autoimmunity.
JumOCA peptide inhibited Il2 mRNA expression relative to β-actin by 10-fold.
OCA-B inhibitor peptide reduces blood glucose and inflammatory cytokine levels in the pancreas in NOD mice with newly arisen diabetes.
JumOCA peptide treatment reduces IFN expressiondecreases CD8+ T cell autoreactivity within the PLNs, similar to genetic OCA-B deletion.

物理化学性质&存储条件

分子量	1391.69
分子式	C60H110N24O14
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Val-Lys-Glu-Leu-Leu-Arg-Arg-Lys-Arg-Gly-His

参考文献

1. Heejoo Kim, et al. J Exp Med. 2021 Mar 1; 218(3): e20200533.

JumOCA peptide (VKELLRRKRGH)

生物&药学活性

物理化学性质&存储条件

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JumOCA peptide (VKELLRRKRGH)

生物&药学活性

物理化学性质&存储条件

参考文献

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