Isobutyl-deoxynyboquinone |CAS:1430798-22-3 Probechem Biochemicals

Chemical Structure : Isobutyl-deoxynyboquinone

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Isobutyl-deoxynyboquinone (IB-DNQ)

货号: PC-62342Not For Human Use, Lab Use Only.

Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner.

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生物&药学活性

Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner.
IB-DNQ has improved solubility and biocompatibility in comparison with DNQ.
IB-DNQ is a superior drug candidate for evaluating anticancer activities and tolerability in vivo.

物理化学性质&存储条件

分子量	326.352
分子式	C18H18N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-isobutyl-4,6-dimethylpyrido[3,2-g]quinoline-2,5,8,10(1H,9H)-tetraone

参考文献

1. Parkinson EI, et al. Acc Chem Res. 2015 Oct 20;48(10):2715-23.

2. Lundberg AP, et al. Invest New Drugs. 2017 Apr;35(2):134-144.

3. Parkinson EI, et al. ACS Chem Biol. 2013 Oct 18;8(10):2173-83.

Isobutyl-deoxynyboquinone (IB-DNQ)

生物&药学活性

物理化学性质&存储条件

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Isobutyl-deoxynyboquinone (IB-DNQ)

生物&药学活性

物理化学性质&存储条件

参考文献

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