Eupatilin | PPARα agonist | Probechem Biochemicals

Chemical Structure : Eupatilin

CAS No.: 22368-21-4

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Eupatilin (NSC 122413, Stillen)

货号: PC-36079Not For Human Use, Lab Use Only.

Eupatilin (NSC 122413, Stillen) is a pharmacologically active flavone derived from Artemisia plants, possess anti-inflammatory, anti-oxidative and anti-cancer activities.

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10 mg	￥1180	In stock
25 mg	￥1980	In stock
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100 mg		Get quote

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生物&药学活性

Eupatilin (NSC 122413, Stillen) is a pharmacologically active flavone derived from Artemisia plants, possess anti-inflammatory, anti-oxidative and anti-cancer activities, is a PPARα agonist.
Eupatilin induces cell cycle arrest in ras-transformed human mammary epithelial cells.
Eupatilin attenuates aortic smooth muscle cell proliferation and migration by inhibiting PI3K, MKK3/6, and MKK4 activities.
Eupatilin inhibits angiogenesis-mediated human hepatocellular metastasis by reducing MMP-2 and VEGF signaling.

物理化学性质&存储条件

分子量	344.32
分子式	C18H16O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one

参考文献

1. Kim DH, et al. Biochem Pharmacol. 2004 Sep 15;68(6):1081-7.

2. Koshihara Y, et al. FEBS Lett. 1983 Jul 11;158(1):41-4.

3. Son JE, et al. Planta Med. 2013 Aug;79(12):1009-16.

4. Park JY, et al. Bioorg Med Chem Lett. 2018 Oct 15;28(19):3150-3154.

Eupatilin (NSC 122413, Stillen)

生物&药学活性

物理化学性质&存储条件

参考文献

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Eupatilin (NSC 122413, Stillen)

生物&药学活性

物理化学性质&存储条件

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