EphB3-IN-1 |CAS:1980036-18-7 Probechem Biochemicals

Chemical Structure : EphB3-IN-1

CAS No.: 1980036-18-7

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EphB3-IN-1

货号: PC-62858Not For Human Use, Lab Use Only.

EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM.

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生物&药学活性

EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM.
EphB3-IN-1 causes foremost inhibition of EphB3 in a panel of 98 kinases, except for RIPK2 and PHKG2.
EphB3-IN-1 abolishes the EphB3 autophosphorylation at Y608 and Y614 at 100 nM.

物理化学性质&存储条件

分子量	363.198
分子式	C16H12Cl2N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-chloro-N-(4-((2-chloro-5-hydroxyphenyl)amino)quinazolin-7-yl)acetamide

参考文献

1. Kung A, et al. J Am Chem Soc. 2016 Aug 24;138(33):10554-60.

EphB3-IN-1

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物理化学性质&存储条件

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