ERX-41 | LIPA inhibitor | Probechem Biochemicals

Chemical Structure : ERX-41

CAS No.: 2440087-54-5

加入收藏

ERX-41 (ERX41)

货号: PC-38797Not For Human Use, Lab Use Only.

ERX-41 is a small molecule that binds to lysosomal acid lipase A (LIPA), and induces endoplasmic reticulum (ER) stress resulting in cell death, blocks proliferation of ER-α⁺ BC cells and TNBC cells in vitro.

规格	价格	库存
5 mg	￥3280	In stock
10 mg	￥5280	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

ERX-41 is a small molecule that binds to lysosomal acid lipase A (LIPA), and induces endoplasmic reticulum (ER) stress resulting in cell death, blocks proliferation of ER-α⁺ BC cells and TNBC cells in vitro.
ERX-41 activity is independent of LIPA lipase function but dependent on its ER localization.
ERX-41 binding of LIPA decreases expression of multiple ER-resident proteins involved in protein folding.
ERX-41 shows no adverse effects either on normal mammary epithelial cells or in mice.

物理化学性质&存储条件

分子量	704.821
分子式	C38H48N4O9
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-hydroxyethoxy)-N-(2-isobutoxy-4-((2-isobutoxy-4-(((1r,4r)-4-methylcyclohexyl)carbamoyl)phenyl)carbamoyl)phenyl)-4-nitrobenzamide

参考文献

1. Liu X, et al. Nat Cancer. 2022 Jun 2. doi: 10.1038/s43018-022-00389-8.

ERX-41 (ERX41)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

ERX-41 (ERX41)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.