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Coumermycin A1

Chemical Structure : Coumermycin A1

CAS No.: 4434-05-3

Coumermycin A1 (C-A1, CA1)

货号: PC-22718Not For Human Use, Lab Use Only.

Coumermycin A1 (C-A1) is a small molecule JAK2 agonist that induces dimerization and activation of JAK2, also inhibits DNA Gyrase and cell division in bacteria.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Coumermycin A1 (C-A1) is a small molecule JAK2 agonist that induces dimerization and activation of JAK2, also inhibits DNA Gyrase and cell division in bacteria.

物理化学性质&存储条件

分子量 1110.08
分子式 C55H59N5O20
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Pyrrole-2,4-dicarboxamide, N2,N4-bis[7-[[6-deoxy-5-C-methyl-4-O-methyl-3-O-[(5-methyl-1H-pyrrol-2-yl)carbonyl]-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-3-methyl-

参考文献

1. Mizuguchi R, et al. J Biol Chem. 1998 Nov 27;273(48):32297-303.

2. Mohi MG, et al. Mol Biol Cell. 1998 Dec;9(12):3299-308.

3. Tieyuan Z, et al. Int Immunopharmacol. 2022 Oct;111:109107.

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