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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-CF101
CF101

Chemical Structure : CF101

CAS No.: 152918-18-8

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CF101 (Piclidenoson, IB-MECA)

货号: PC-22193Not For Human Use, Lab Use Only.

Piclidenoson (IB-MECA, CF101) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist, shows antiproliferative effect and induces apoptosis in multiple cancer cell types like melanoma, leukemia.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Piclidenoson (IB-MECA, CF101) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist, shows antiproliferative effect and induces apoptosis in multiple cancer cell types like melanoma, leukemia.

物理化学性质&存储条件

分子量 510.29
分子式 C18H19IN6O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S,3S,4R,5R)-3,4-Dihydroxy-5-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide

参考文献

1. Hofer M, et al. Radiat Environ Biophys. 2014 Mar;53(1):211-215.

2. Abedi H, et al. Tumour Biol. 2014 Nov;35(11):11027-11039.

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