CBB3001 | LSD1 inhibitor | Probechem Biochemicals

Chemical Structure : CBB3001

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CBB3001 (CBB-3001, CBB 3001)

货号: PC-35295Not For Human Use, Lab Use Only.

CBB3001 (CBB-3001) is a novel potent, selective histone demethylase LSD1 inhibitor with IC50 of 21.25 uM.

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生物&药学活性

CBB3001 (CBB-3001) is a potent, selective histone demethylase LSD1 inhibitor with IC50 of 21.25 uM.
CBB3001 potently inhibits LSD1 activity both in vitro and in vivo.
CBB3001 also selectively inhibits the growth of human ovarian teratocarcinoma PA-1 and mouse embryonic carcinoma F9 cells.
CBB3001 caused the downregulation of pluripotent stem cell proteins SOX2 and OCT4, does not have significant inhibition on the growth of human colorectal carcinoma HCT116 cells or mouse fibroblast NIH3T3 cells that do not express these stem cell proteins.

物理化学性质&存储条件

分子量	349.427
分子式	C19H27NO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-butyl 2-(4-(tert-butoxycarbonyloxy)phenyl)cyclopropylcarbamate

参考文献

1. Hoang N, et al. Bioorg Med Chem. 2018 May 1;26(8):1523-1537.

CBB3001 (CBB-3001, CBB 3001)

生物&药学活性

物理化学性质&存储条件

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CBB3001 (CBB-3001, CBB 3001)

生物&药学活性

物理化学性质&存储条件

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