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首页-小分子抑制剂&激动剂-Others-Other Targets-BCAT1 inhibitor 2
BCAT1 inhibitor 2

Chemical Structure : BCAT1 inhibitor 2

CAS No.: 406191-34-2

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BCAT1 inhibitor 2 (Bi2, BCATc inhibitor 2)

货号: PC-22799Not For Human Use, Lab Use Only.

BCAT1 inhibitor 2 (Bi2) is a specific inhibitor of cytosolic branched-chain aminotransferase (BCATc, BCAT1) with IC50 of 0.2/ 0.8 uM for rat/human BCATc respectively, weakly inhibits rat mitochondrial isoenzyme rBCATm.

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5 mg ￥1380 In stock
10 mg ￥2180 In stock
25 mg ￥3680 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BCAT1 inhibitor 2 (Bi2) is a specific inhibitor of cytosolic branched-chain aminotransferase (BCATc, BCAT1) with IC50 of 0.2/ 0.8 uM for rat/human BCATc respectively, weakly inhibits rat mitochondrial isoenzyme rBCATm.

物理化学性质&存储条件

分子量 418.77
分子式 C16H10ClF3N2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-chloro-N'-[2-(trifluoromethyl)phenyl]sulfonyl-1-benzofuran-2-carbohydrazide

参考文献

1. Caballero, J., et al. Mol. Divers 13, 493–500 (2009).

2. Lain-Yen Hu, et al. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40.

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