Aurora A-IN-10 |CAS:1158838-45-9 Probechem Biochemicals

Chemical Structure : Aurora A-IN-10

CAS No.: 1158838-45-9

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Aurora A-IN-10

货号: PC-45948Not For Human Use, Lab Use Only.

A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM.

规格	价格	库存
10 mg	￥1040	In stock
50 mg	￥3280	In stock
100 mg	￥5880	In stock

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生物&药学活性

A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM; displays >1,000-fold selectivity over Aurora B (IC50=3.4 uM) or CDKs; A useful tool compound for investigating the cellular role of Aurora A kinases without the complication of also inhibiting Aurora B.

物理化学性质&存储条件

分子量	588.075
分子式	C31H31ClFN7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, N-(2-chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-

参考文献

1. Aliagas-Martin I, et al. J Med Chem. 2009 May 28;52(10):3300-7.

Aurora A-IN-10

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物理化学性质&存储条件

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Aurora A-IN-10

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物理化学性质&存储条件

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