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首页-抗体和重组蛋白-Biosimilar Antibody-Atezolizumab
Atezolizumab

Chemical Structure : Atezolizumab

CAS No.: 1380723-44-3

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Atezolizumab (Anti-human PD-L1 mAb, human IgG1 N297A-Kappa)

货号: PC-Ab1004Not For Human Use, Lab Use Only.

A humanized monoclonal antibody to programmed death-ligand 1 (PD-L1) that increases immune reactivity to tumor neoantigens and is used as immunotherapy of selected cancers of the bladder and lung. increases immune reactivity to tumor neoantigens and is used as immunotherapy of selected cancers of the bladder and lung. Atezolizumab has been associated with a low rate of serum enzyme elevations during therapy and with uncommon instances of clinically apparent, immune-mediated liver injury..

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A humanized monoclonal antibody to programmed death-ligand 1 (PD-L1) that increases immune reactivity to tumor neoantigens and is used as immunotherapy of selected cancers of the bladder and lung. increases immune reactivity to tumor neoantigens and is used as immunotherapy of selected cancers of the bladder and lung. Atezolizumab has been associated with a low rate of serum enzyme elevations during therapy and with uncommon instances of clinically apparent, immune-mediated liver injury.

物理化学性质&存储条件

分子量
分子式 Human IgG1 N297A-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Atezolizumab; MPDL 3280A; MPDL3280A; programmed death-1; programmed death 1; Anti-human PD1; PD 1; Programmed cell death protein 1; hPD-1; hPD1; hPD 1; hPD-L1;PD-L1

参考文献

1. 1, Schmid P, et al. N Engl J Med. 2018 Nov 29;379(22):2108-2121. 2, Herbst RS, et al. N Engl J Med. 2020 Oct 1;383(14):1328-1339. 3, Powles T, et al. Nature. 2014 Nov 27;515(7528):558-62.

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