Chemical Structure : Angiotensin 1-7
CAS No.: 51833-78-4
货号: PC-43019Not For Human Use, Lab Use Only.
Angiotensin (1-7) (Ang-(1-7)) is an active heptapeptide of the Renin-angiotensin system (RAS), inhibits purified canine angiotensin converting enzyme (ACE) activity with IC50 of 0.65 uM.
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---|---|---|---|
10 mg | ¥580 | In stock | |
25 mg | ¥980 | In stock | |
50 mg | ¥1480 | In stock | |
100 mg | Get quote |
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Angiotensin (1-7) ((Ang-(1-7), Talfirastide) is an active heptapeptide of the Renin-angiotensin system (RAS), inhibits purified canine angiotensin converting enzyme (ACE) activity with IC50 of 0.65 uM.
Angiotensin (1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide, abolishes AGE-induced cellular hypertrophy and myofibroblast transformation via inhibition of ERK1/2.
Angiotensin (1-7) evokes anti-arrhythmogenic effects in animal models, upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats.
分子量 | 899.0048 | |
分子式 | C41H62N12O11 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
H2O: ≥ 30.2 mg/mL |
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Chemical Name/SMILES |
1-7-Angiotensin II, 5-L-isoleucine- |
1. Li P, et al. Hypertension. 1997 Jan;29(1 Pt 2):394-400.
2. Alzayadneh EM, et al. Cell Signal. 2014 Dec;26(12):3027-35.
3. Averill DB, et al. Circulation. 2003 Oct 28;108(17):2141-6.
4. Costa MA, et al. Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1205-11.
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