Ampalex (CX516) | AMPAR PAM | Probechem Biochemicals

Chemical Structure : Ampalex

CAS No.: 154235-83-3

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Ampalex (CX516, BDP 12, Ampakine CX516)

货号: PC-42743Not For Human Use, Lab Use Only.

Ampalex (CX516) is a positive allosteric modulator of AMPA, increases fast, excitatory (glutamatergic) synaptic responses in hippocampal slices by about 50% with an EC50 of 170 uM.

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Ampalex (CX516) is a positive allosteric modulator of AMPA, increases fast, excitatory (glutamatergic) synaptic responses in hippocampal slices by about 50% with an EC50 of 170 uM.
Ampalex (CX516) increases the potency of the glutamate concentration-response profile by 3-fold.

物理化学性质&存储条件

分子量	241.2884
分子式	C14H15N3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 41 mg/mL
Chemical Name/SMILES	Methanone, 1-piperidinyl-6-quinoxalinyl-

参考文献

1. Arai A, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):627-38.

2. Hampson RE, et al. J Neurosci. 1998 Apr 1;18(7):2740-7.

3. Baumbarger PJ, et al. J Pharmacol Exp Ther. 2001 Jul;298(1):86-102.

Ampalex (CX516, BDP 12, Ampakine CX516)

生物&药学活性

物理化学性质&存储条件

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Ampalex (CX516, BDP 12, Ampakine CX516)

生物&药学活性

物理化学性质&存储条件

参考文献

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