欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-小分子抑制剂&激动剂-NF-κB Pathway-NF-κB-(R)-(-)-Ibuprofen
(R)-(-)-Ibuprofen

Chemical Structure : (R)-(-)-Ibuprofen

CAS No.: 51146-57-7

(R)-(-)-Ibuprofen ((R)-Ibuprofen)

货号: PC-45990Not For Human Use, Lab Use Only.

An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
250 mg Get quote

大包装,大折扣!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids; inhibits NF-κB activation (IC50=121.8 uM) in response to T-cell stimulation as well as block superoxide formation, β-glucuronidase release, and LTB4 generation by stimulated neutrophils (IC50 =40-100 uM).

Pain

Approved

物理化学性质&存储条件

分子量 206.2808
分子式 C13H18O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-,(αR)-

参考文献

1. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.

2. Evans AM. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14.

3. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.

备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: