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首页-小分子抑制剂&激动剂-Apoptosis-PKD-kb-NB142-70
kb-NB142-70

Chemical Structure : kb-NB142-70

CAS No.: 1233533-04-4

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kb-NB142-70 (kb NB 142-70)

货号: PC-63036Not For Human Use, Lab Use Only.

kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM.

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10 mg ￥1280 In stock
25 mg ￥1980 In stock
50 mg ￥3280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM.
kb NB142 70 displays 10-fold increase in the in vitro PKD1 inhibitory potency versus CID755673.
kb NB142 70 inhibits PC-3, PANC-1, CFPAC-1 cellular growth with IC50 of 5-30 uM.

物理化学性质&存储条件

分子量 251.318
分子式 C11H9NO2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3,4-dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one

参考文献

1. Bravo-Altamirano K, et al. ACS Med Chem Lett. 2011 Feb 14;2(2):154-159.

2. Guo J, et al. Cancer Chemother Pharmacol. 2013 Feb;71(2):331-44.

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