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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-XEN-402
XEN-402

Chemical Structure : XEN-402

CAS No.: 1259933-16-8

XEN-402 (Funapide;TV-45070)

货号: PC-61869Not For Human Use, Lab Use Only.

XEN-402 (Funapide,TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

XEN-402 (Funapide, TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain.

物理化学性质&存储条件

分子量 429.35
分子式 C22H14F3NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3'S)-1'-{[5-(trifluoromethyl)furan-2-yl]methyl}-2H,6H-spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

参考文献

1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.

2. Goldberg YP, et al. Pain. 2012 Jan;153(1):80-5.

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