VAS-2870 |CAS:722456-31-7 Probechem Biochemicals

Chemical Structure : VAS-2870

CAS No.: 722456-31-7

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VAS-2870 (VAS2870;VAS 2870)

货号: PC-60724Not For Human Use, Lab Use Only.

VAS2870 (VAS-2870) potent, specific NADPH oxidase (Nox) inhibitor, completely abolishes PDGF-mediated NAD(P)H oxidase activation and ROS production at 10-20 uM in vascular smooth muscle cells (VSMC).

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1880	In stock
50 mg	￥2980	In stock
100 mg		Get quote

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生物&药学活性

VAS2870 (VAS-2870) potent, specific NADPH oxidase (Nox) inhibitor, completely abolishes PDGF-mediated NAD(P)H oxidase activation and ROS production at 10-20 uM in vascular smooth muscle cells (VSMC).
VAS-2870 abrogates thalidomide stimulation of cardiomyogenesis;
VAS-2870 also impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells.

物理化学性质&存储条件

分子量	360.395
分子式	C18H12N6OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine

参考文献

1. ten Freyhaus H, et al. Cardiovasc Res. 2006 Jul 15;71(2):331-41.

2. Stielow C, et al. Biochem Biophys Res Commun. 2006 May 26;344(1):200-5.

3. Sancho P, et al. Biochem Pharmacol. 2011 Apr 1;81(7):917-24.

4. Kleinschnitz C, et al. PLoS Biol. 2010 Sep 21;8(9). pii: e1000479.

VAS-2870 (VAS2870;VAS 2870)

生物&药学活性

物理化学性质&存储条件

参考文献

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VAS-2870 (VAS2870;VAS 2870)

生物&药学活性

物理化学性质&存储条件

参考文献

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