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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-E3 Ubiquitin Ligase-Skp2-IN-C1
Skp2-IN-C1

Chemical Structure : Skp2-IN-C1

CAS No.: 432001-69-9

Skp2-IN-C1 (CKS1i)

货号: PC-62453Not For Human Use, Lab Use Only.

Skp2-IN-C1 is a specific small molecule inhibitor of Skp2-mediated p27 degradation, induces p27 accumulation in a Skp2-dependent manner and promoted cell-type-specific blocks in the G1 or G2/M phases.

规格 价格 库存 数量
10 mg ¥1280 In stock
25 mg ¥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Skp2-IN-C1 is a specific small molecule inhibitor of Skp2-mediated p27 degradation, induces p27 accumulation in a Skp2-dependent manner and promoted cell-type-specific blocks in the G1 or G2/M phases.

物理化学性质&存储条件

分子量 465.336
分子式 C18H13BrN2O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-2-(4-bromo-2-((4-oxo-3-(pyridin-3-ylmethyl)-2-thioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid

参考文献

1. Wu L, et al. Chem Biol. 2012 Dec 21;19(12):1515-24.

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