Sobetirome (QRX-431) | TRβ1 agonist | Probechem Biochemicals

Chemical Structure : QRX-431

CAS No.: 211110-63-3

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QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431)

货号: PC-20362Not For Human Use, Lab Use Only.

QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431) is a TRβ1-selective thyromimetic, selectively binds to TRβ over TRα with Kd values of 0.1 and 1.8 nM, respectively.

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5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
50 mg	￥4280	In stock
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生物&药学活性

QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431) is a TRβ1-selective thyromimetic, selectively binds to TRβ over TRα with Kd values of 0.1 and 1.8 nM, respectively.

物理化学性质&存储条件

分子量	328.41
分子式	C20H24O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-(4-hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetic acid

参考文献

1. Trost SU, et al. Endocrinology. 2000 Sep;141(9):3057-64.

2. Ribeiro MO, et al. J Clin Invest. 2001 Jul;108(1):97-105.

QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431)

生物&药学活性

物理化学性质&存储条件

参考文献

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QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431)

生物&药学活性

物理化学性质&存储条件

参考文献

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