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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-E3 Ubiquitin Ligase-PRT-4165
PRT-4165

Chemical Structure : PRT-4165

CAS No.: 31083-55-3

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PRT-4165 (NSC-600157)

货号: PC-45731Not For Human Use, Lab Use Only.

PRT-4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation, inhibits the E3 ubiquitin ligase activity of PRC1, but not RNF8.

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10 mg ￥1580 In stock
25 mg ￥2580 In stock
50 mg ￥3980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PRT-4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation, inhibits the E3 ubiquitin ligase activity of PRC1, but not RNF8.
PRT-4165 inhibits double-strand breaks (DSBs) repair.

物理化学性质&存储条件

分子量 235.2375
分子式 C15H9NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1H-Indene-1,3(2H)-dione, 2-(3-pyridinylmethylene)-

参考文献

1. Ismail IH, et al. J Biol Chem. 2013 Sep 13;288(37):26944-54.

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