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Necrocide-1

Chemical Structure : Necrocide-1

CAS No.: 1247028-61-0

Necrocide-1 (Necrocide 1, NC1)

货号: PC-23519Not For Human Use, Lab Use Only.

Necrocide-1 (NC1) is a small molecule inducer of tumor necrosis factor (TNF)-independent necrosis, shows antiproliferative activity with IC50 values of 0.48 and 2 nM for MCF-7 and PC3, respectively

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Necrocide-1 (NC1) is a small molecule inducer of tumor necrosis factor (TNF)-independent necrosis, shows antiproliferative activity with IC50 values of 0.48 and 2 nM for MCF-7 and PC3, respectively

物理化学性质&存储条件

分子量 365.47
分子式 C23H27NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2H-Indol-2-one, 3-cycloheptyl-1,3-dihydro-3-(4-hydroxyphenyl)-6-Methoxy-7-Methyl-, (3S)-

参考文献

1. Jing Zhang, et al. Cell Death Dis. 2023 Apr 5;14(4):238.

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