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首页-小分子抑制剂&激动剂-Apoptosis-TNF-alpha-Mitochonic Acid 35
Mitochonic Acid 35

Chemical Structure : Mitochonic Acid 35

CAS No.: 1611470-23-5

Mitochonic Acid 35 (MA-35;MA35;MA 35)

货号: PC-60273Not For Human Use, Lab Use Only.

A dual inhibitor of TNF-α and TGF-β1 by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.

规格 价格 库存 数量
25 mg Get quote
100 mg Get quote
250 mg Get quote
1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

A dual inhibitor of TNF-α and TGF-β1 by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation; attenuates the LPS/GaIN-induced hepatic inflammation in the mice, and downregulates TGF-β1-induced fibrotic gene expression; attenuates renal inflammation and fibrosis with the downregulation of inflammatory cytokines and fibrotic gene expressions in renal fibrosis model.

物理化学性质&存储条件

分子量 341.36
分子式 C19H19NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(3, 5-dimethoxybenzyloxy)-3-indoleacetic acid

参考文献

1. Shima H, et al. Sci Rep. 2017 May 15;7(1):1884.

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